A Systematic Approach to Medically Unexplained Symptoms is an educational conference at Loews Coronado Bay Resort in Coronado, California, that focuses on practical, multidisciplinary strategies for assessing and managing medically unexplained symptoms. The program brings together clinicians, mental health professionals, and researchers to present evidence-based frameworks, clinical assessment tools, and communication approaches for improving diagnosis and patient care. It is notable for emphasizing a systematic biopsychosocial approach to complex symptom presentations and for promoting interdisciplinary collaboration in clinical practice.